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Volume 109, Issue 8, Pages 705-707 (October 2007)


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Superficial siderosis due to a lumbar ependymoma mimicking adult-onset spinocerebellar ataxia

Konstantinos SpengosCorresponding Author Informationemail address, Sofia Vassilopoulou, Georgios Tsivgoulis, Georgios Karachalios, Demetris Vassilopoulos

Received 29 November 2006; received in revised form 26 April 2007; accepted 29 April 2007.

Abstract 

Superficial siderosis (SS), as a result of chronic subarachnoid haemorrhage and haemosiderin deposition on the leptomeninges and subpial layers of the brain, cerebellum and spinal cord, can cause ataxia, pyramidal tract lesions and hearing deficits. In cases with not pronounced hearing impairment adult-onset spinocereballar ataxia can be considered as a differential diagnostic alternative. We report a similar case where the diagnosis of SS was established by means of gradient echo MRI sequences 5 years after symptom onset. A bleeding lumbar ependymoma was identified as a source of haemorrhage. Surgical tumor resection stopped any further disease progression. Our report underlines that clinicians should be aware of the clinical features and diagnostic pitfalls of SS. Time of diagnosis and neurosurgical intervention can essentially influence the patients’ prognosis.

University of Athens, School of Medicine, Department of Neurology, Eginition Hospital, Athens, Greece

Corresponding Author InformationCorresponding author at: Department of Neurology, Vas. Sofias 82, 11528 Athens, Greece. Tel.: +30 6946466216; fax: +30 2106742604.

PII: S0303-8467(07)00115-1

doi:10.1016/j.clineuro.2007.04.015


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