Clinical Neurology and Neurosurgery
Volume 111, Issue 10 , Pages 795-800 , December 2009

Ultrastructure and immunohistochemistry of the trigeminal peripheral myelinated axons in patients with neuralgia

  • Slobodan Marinković

      Affiliations

    • Institute of Anatomy, School of Medicine, Belgrade, Serbia
    • Corresponding Author InformationCorresponding author. Tel.: +81 265 82 2121; fax: +81 265 82 2118.
    • ,
  • Hirohiko Gibo

      Affiliations

    • Neurosurgical Service (SIGNS), Showa-Inan General Hospital, Komagane City, Japan
    • ,
  • Vera Todorović

      Affiliations

    • Institute for Medical Research, Department of Immunohistochemistry and Electron Microscopy, Belgrade, Serbia
    • ,
  • Branislav Antić

      Affiliations

    • Military Medical Academy, Belgrade, Serbia
    • ,
  • Dragoslava Kovačević

      Affiliations

    • Department of Ophthalmology, University Clinical Center of Serbia, Belgrade, Serbia
    • ,
  • Milan Milisavljević

      Affiliations

    • Institute of Anatomy, School of Medicine, Belgrade, Serbia
    • ,
  • Mila Ćetković

      Affiliations

    • Department of Histology and Embryology, School of Medicine, Belgrade, Serbia

Received 3 July 2008 ,Revised 22 July 2009 ,Accepted 25 July 2009.

References 

  1. Adams RD, Victor MV. Principles of neurology. New York: McGraw-Hill, Inc.; 1993;p. 1170–83
  2. Devor M, Govrin-Lippmann R, Rappaport HZ. Mechanism of trigeminal neuralgia: an ultrastructural analysis of trigeminal root specimens obtained during microvascular decompression surgery. J Neurosurg. 2002;96:532–543
  3. Moore KR, Burchiel KJ. Surgical management of trigeminal neuralgia. In:  Tindall GT,  Cooper PR,  Barrow DL editor. The practice of neurosurgery. vol. 3:Baltimore: Williams & Wilkins; 1996;p. 3043–3064
  4. Haines SJ, Jannetta PJ, Zorub DS. Microvascular relations of the trigeminal nerve. An anatomical study with clinical correlation. J Neurosurg. 1980;42:381–386
  5. Hamlyn PJ. Neurovascular compression of the lower cranial nerves. Amsterdam: Elsevier; 1999;p. 75–118
  6. Jannetta PJ. Arterial compression of the trigeminal nerve at the pons in patients with trigeminal neuralgia. J Neurosurg. 1967;26(Suppl.):159–162
  7. Choudhari KA. Quadriple vessel involvement at root entry zone in trigeminal neuralgia. Clin Neurol Neurosurg. 2007;109:203–205
  8. Burchiel KJ, Clarke H, Haglund M, Loeser JD. Long-term efficacy of microvascular decompression in trigeminal neuralgia. J Neurosurg. 1988;69:35–38
  9. Chen J-F, Lee S-T. Comparison of percutaneous trigeminal ganglion compression and microvascular decompression for the management of trigeminal neuralgia. Clin Neurol Neurosurg. 2003;105:203–208
  10. Rappaport HZ, Govrin-Lippmann R, Devor M. An electron-microscopic analysis of biopsy samples of the trigeminal root taken during microvascular decompressive surgery. Stereotact Funct Neurosurg. 1997;68:182–186
  11. Hilton DA, Love S, Gradidge T, Coakham HB. Pathological findings associated with trigeminal neuralgia caused by vascular compression. Neurosurgery. 1994;35:299–303
  12. Love S, Coakham HB. Trigeminal neuralgia. Pathology and pathogenesis. Brain. 2001;124:2347–2360
  13. Beavor DL. Electron microscopy of the gasserian ganglion in trigeminal neuralgia. J Neurosurg. 1967;26(Suppl.):138–150
  14. Kerr FWL. Pathology of trigeminal neuralgia: light and electron microscopic observations. J Neurosurg. 1967;26(Suppl.):151–156
  15. Kerr FW, Miller RH. The pathology of trigeminal neuralgia. Electron microscopic studies. Arch Neurol. 1966;15:308–319
  16. Love S, Hilton DA, Coakham HB. Central demyelination of the Vth nerve root in trigeminal neuralgia associated with vascular compression. Brain Pathol. 1998;8:1–12
  17. Bohl J, Goebel HH. Pathology of the peripheral nervous system. In:  Cervós-Navarro J,  Ferszt R editor. Clinical neuropathology. Stuttgart: Georg Thieme Verlag; 1989;p. 401–456
  18. Compston DAS, Cuzner ML, Davison AN. Clinical features and pathophysiology of demyelinating diseases. In:  Bachelard HS,  Lunt GG,  Marsden DC editor. Clinical neurochemistry. vol. 2:London: Academic Press, Harcourt Brace Jovanovich, Publishers; 1986;p. 75–189
  19. Johnson PC. Peripheral nerve pathology. In:  Davis RL,  Robertson DM editor. Textbook of neuropathology. Baltimore: Williams & Wilkins; 1997;p. 1233–1324
  20. Mackinnon SE, Dellon AL, Hudson AR, Hunter DA. Chronic human nerve compression—a histological assessment. Neuropathol Appl Neurobiol. 1986;12:547–565
  21. Pleasure D. Biochemistry of neuropathy. In:  Siegel GJ,  Agranoff BW,  Albers WR,  Molinoff BP editor. Basic neurochemistry. Molecular, cellular, and medical aspects. New York: Raven Press; 1989;p. 685–696
  22. Raine CS. Demyelinating diseases. In:  Davis RL,  Robertson DM editor. Textbook of neuropathology. Baltimore: Williams & Wilkins; 1997;p. 627–714
  23. Schröder JM. Pathology of peripheral nerves. An atlas of structural molecular pathological changes. Berlin: Springer; 2001;p. 65–306
  24. Miller K. Immunocytochemical techniques. In:  Bancroft JD,  Gamble M editor. Theory and practice of histological techniques. 5th edn.. London: Churchil Livingstone; 2002;p. 421–464
  25. Hirano A. Neurons and astrocytes. In:  Davis RL,  Robertson DM editor. Textbook of neuropathology. Baltimore: Williams & Wilkins; 1997;p. 1–109
  26. Peters A, Palay SL, Webster HdeF. The fine structure of the nervous system. The Neurons and supporting cells. Philadelphia: W.B. Saunders Company; 1976;p. 90–263
  27. Lang J. Clinical anatomy of the posterior cranial fossa and its foramina. Stuttgart: Georg Thieme Verlag; 1991;p. 83–92
  28. Ziyal IM, Sekhar LN, Özgen T, Söylemeyoğlu F, Alpter M, Beşer M. The trigeminal nerve and ganglion: an anatomical, histological, and radiological study addressing the transtrigeminal approach. Surg Neurol. 2004;61:564–573
  29. Hamlyn PJ, King TT. Neurovascular compression in trigeminal neuralgia: a clinical and anatomical study. J Neurosurg. 1992;76:948–954
  30. Jamjoom AB, Jamjoom ZAB, Al-Fehaily M, El-Watidy S, Al-Moallem M, Rahman NU. Trigeminal neuralgia related to cerebellopontine angle tumors. Neurosurg Rev. 1996;19:237–334
  31. McCormick DA. Membrane properties and neurotransmitter action. In:  Shepherd GM editors. The synaptic organization of the brain. New York: Oxford University Press; 1994;p. 32–66
  32. Cherkas PS, Huang TY, Pannicke T, Tal M, Reichenbach A, Hanani M. The effects of axotomy on neurons and satellite glial cells in mouse trigeminal ganglion. Pain. 2004;110:290–298
  33. Nieuwenhuys R. Chemoarchitecture of the brain. Berlin: Springer-Verlag; 1985;p. 7–113
  34. Quartu M, Diaz G, Floris A, Lai ML, Priestley JV, Del Fiacco M. Calcitonin gene-related peptide in the human trigeminal sensory system at developmental and adult life stages: immunohistochemistry, neuronal morphometry and coexistence with substance P. J Chem Neuroanat. 1992;5:143–157
  35. Raine CS. Oligodendrocytes and central nervous system myelin. In:  Davis RL,  Robertson DM editor. Textbook of neuropathology. Baltimore: Williams & Wilkins; 1997;p. 137–164
  36. Ishikawa M, Nishi S, Aoki T, Takase T, Wada E, Ohwaki H, et al. On cases of trigeminal neuralgia without vascular compression: proposal of a different mechanism. J Clin Neurosci. 2002;9:200–204
  37. Marinković S, Todorović V, Gibo H, Budeč M, Drndarević N, Pešić D, et al. The trigeminal vasculature pathology in patients with neuralgia. Headache. 2007;47:1334–1339

PII: S0303-8467(09)00191-7

doi: 10.1016/j.clineuro.2009.07.020

Clinical Neurology and Neurosurgery
Volume 111, Issue 10 , Pages 795-800 , December 2009

Article Tools

* Image Usage & Resolution