Clinical Neurology and Neurosurgery
Volume 111, Issue 10 , Pages 889-892, December 2009

Neuro-Behcet's disease presenting with amnesia and frontal dysfunction

  • Masaru Mimura

      Affiliations

    • Department of Neuropsychiatry, Showa University School of Medicine, 5-11-11 Kita-Karasuyama, Setagaya-ku, Tokyo 157-8577, Japan
    • Corresponding Author InformationCorresponding author at: Department of Neuropsychiatry, Showa University School of Medicine, 6-11-11 Kita-Karasuyama, Setagaya-ku, Tokyo 157-8577, Japan. Tel.: +81 3 3300 5232; fax: +81 3 3308 1710.
  • ,
  • Motoichiro Kato

      Affiliations

    • Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan
  • ,
  • Haruo Kashima

      Affiliations

    • Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan

Received 28 September 2008; received in revised form 4 August 2009; accepted 6 August 2009.

Abstract 

We report a 48-year-old patient with neuro-Behcet's disease who presented with the combination of severe memory impairment and frontal/executive dysfunction. The clinical feature mimicked that of diencephalic amnesic syndrome. The MRI and SPECT findings supported the notion that the thalamus and related subcortical–frontal connection was responsible for this patient's problem.

Keywords: Neuro-Behcet's disease, Amnesia, Frontal dysfunction, SPECT

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PII: S0303-8467(09)00205-4

doi:10.1016/j.clineuro.2009.08.002

Clinical Neurology and Neurosurgery
Volume 111, Issue 10 , Pages 889-892, December 2009