Stereotactic brain biopsy: Single center retrospective analysis of complications
Received 4 March 2009; received in revised form 13 August 2009; accepted 15 August 2009.
Abstract
Objective
Stereotactic biopsy is a widely used surgical technique for the histological diagnosis of intracranial lesions. Potential risks of this procedure, such as hemorrhage, seizure, and infection have been established, and different risk factors have been characterized. However, these risks have been addressed by only few studies conducted in Asian countries.
Materials and methods
The study group is comprised of 299 consecutive stereotactic biopsy procedures by 11 neurosurgeons between 2004 and 2007. The pre-operative medical conditions, methods of biopsy and postoperative complications were analyzed.
Result
The overall diagnostic yield was 90.64%. Complications were observed in 7.36% of the cases, with symptomatic hemorrhages occurring in 4.35% of the cases, and the overall mortality rate in this study population was 1.34%. Patients with liver cirrhosis were at a higher risk of hemorrhage. Other clinical, radiological, or histological variables were not associated with an increased risk of complications.
Conclusion
Stereotactic brain biopsy is a safe and reliable way to obtain a histological diagnosis. Based on our recent clinical experiences, the data suggests that more attention should be paid to liver cirrhotic patients, since the chance on hemorrhage is significantly larger.
Department of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung Medical College and University, 5, Fu-Shin Street, Kwei-Shan, Tao-Yuan County, Linkou 333, Taiwan
ABSTRACT